

MUSE DEFINITION SOFTWARE
Overview of software changes affecting ICD-10 The second most significant leading causes of death change was Parkinson's disease with a net gain of 3%, which mostly corresponded with a net loss of 4% from Acute respiratory infections other than influenza and pneumonia.Ģ. The most significant leading causes of death change was Disorders of fluid electrolyte and acid-based balance (dehydration) which had a net loss of 44%, which mostly corresponded with a net gain of 24% to Mental and behavioural disorders due to psychoactive substance use. There are five leading causes of death with strong evidence of change in the frequency that the underlying causes of death falls within them and a further 11 with evidence of change.

There are two ICD-10 chapters with strong evidence of change in the frequency that the underlying causes of death falls within them Chapter I Certain infectious and parasitic diseases decreased by 4% between the two versions and Chapter VI Diseases of the nervous system increased by 1%. This is less than half of the change observed when we switched from IRIS 4.2.3 to MUSE 5.5 in 2020. When comparing a sample of deaths dual coded using the previous Multi-causal and Uni-causal Selection Engine (MUSE) 5.5 and the updated MUSE 5.8 version, 99.2% of underlying causes of death remained in the same International Classification of Diseases, Tenth Revision (ICD-10) chapter designation, and 98.6% remained in the same leading cause of death designation.
